Diastereoselective Synthesis of β‐Nitro‐ and β‐Aminoalcohols

Almost pure diastereoisomers of β-amino alcohols, important as synthons, can be prepared via the O-silylated nitroalcohols (1). Compounds (1) are accessible by protonation of the corresponding lithium salts or by addition of silylated aci-nitro derivatives R2CH = NO2Si tBuMe2 to aldehydes R1CHO.