Key points are not available for this paper at this time.
Design
Review
Supports rigorous antiemetic trial design; leaves open optimal endpoints and selection criteria for future studies.
Studies of antiemetics require consideration of methodologic issues that may not be of concern in trials of antineoplastics. This paper illustrates how the strength of the results of these studies can be affected by (1) the types of patients studied, (2) the sample size, (3) the trial design, (4) the choice and definition of outcome measures, and (5) the method of analysis.
No takes yet. Share an insight, caveat, or question.
Pater et al. (1984) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: