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Xerostomia provoked in rats by surgical removal of the major salivary glands favoured the development of oral candidiasis. After 32 weeks of inoculation, 20% of normal and 70% of xerostomic rats showed candidal infection on the tongue but only in xerostomic rats did candidiasis affect the pharyngeal aspect of the tongue.
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Jorge et al. (1993) studied this question.
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