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A case of a 38‐year‐old woman with a mastocytosis syndrome is presented. The urinary excretion of histamine, methylhistamine and 1‐methyl‐4‐imidazole acetic acid was considerably higher than normally. Treatment with l ‐hyoscyamine sulphate abolished gastritis, diarrhoea and pressure‐induced pain, and reduced dermographism and itching. However, there was no effect on the abnormal urinary histamine excretion.
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Berg et al. (1968) studied this question.
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