Key result
Age ≥65 linked to ~5-fold higher rate of upper GI bleeding during stroke rehab.
Cohort (n=568)
No
BACKGROUND: Stroke complications can occur not only in the acute ward but also during the subsequent rehabilitation period. However, existing studies have not adequately addressed the incidence of various complications among stroke in patients undergoing rehabilitation using a longitudinal method. We aimed to investigate the longitudinal impact of age on complication rates in patients undergoing inpatient stroke rehabilitation at different disease stages. METHODS: Five hundred and sixty-eight first-time stroke patients transferred to the rehabilitation ward between July 2002 and June 2012 were included in the study. Patients were stratified into age groups for comparison: <65 years (young), 65 years to <75 years (younger old), and ≥75 years (older old). In total, 30 different complication types were recorded for analysis. RESULTS: Constipation, shoulder pain, symptomatic urinary tract infection (UTI), and fever were common complications during initial stay in the rehabilitation ward, and incidence was >10% in all three age groups. The frequency of incidence of upper gastrointestinal bleeding (UGIB) was higher in the younger old (17.9%) and older old (20.6%) groups than in the young group (4.1%) during initial stay in the rehabilitation ward (p < 0.001). The incidence of UGIB was higher in the younger old (8.04%) and older old (8.33%) groups than in the young group (0.19%) during subsequent stay in the rehabilitation ward (p = 0.011). The incidence of symptomatic UTI was higher in the younger old (21.0%) and older old (20.0%) groups than in the young group (11.5%) during initial stay in the rehabilitation ward (p = 0.019). The incidence of symptomatic UTI was higher in the older old group (29.17%) than in the younger old (9.21%) and young (3.14%) groups during subsequent stay in the rehabilitation ward (p < 0.001). CONCLUSIONS: Age does not affect every complication type. UGIB and symptomatic UTI occurred more frequently in stroke patients aged ≥65 years during their stay in the rehabilitation ward.
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Chen et al. (2014) conducted a cohort in First-time stroke undergoing inpatient rehabilitation (n=568). Older age (65 to <75 years and ≥75 years) vs. Younger age (<65 years) was evaluated on Incidence of upper gastrointestinal bleeding (UGIB) during initial rehabilitation stay (p=<0.001). Age ≥65 years was associated with higher rates of upper gastrointestinal bleeding (17.9%-20.6% vs 4.1%, p<0.001) and symptomatic UTI (20.0%-21.0% vs 11.5%, p=0.019) during initial stroke rehab.
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