Why the study?
Does serum sodium concentration predict the risk of stroke and major ischaemic heart disease in middle-aged males?
Does serum sodium concentration predict the risk of stroke and major ischaemic heart disease in middle-aged males?
Serum sodium concentration is inversely related to the risk of stroke up to 144 mmol/l in middle-aged males, suggesting that variations within the normal range may impact stroke risk.
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Serum sodium in upper-normal range associated with lower stroke risk in middle-aged males; hypothesis-generating and requires prospective confirmation before clinical consideration.
Wannamethee et al. (1994) studied this question.
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