Why the study?
Complication rates remain high following TAVI, making the identification of preoperative factors predictive of postoperative adverse outcomes an important strategy to avoid complications and reduce costs.
Identifying specific pre-operative, procedural, and post-operative risk factors can optimize multidisciplinary patient selection and mitigate adverse outcomes following TAVI.
With the advent of Transcatheter Aortic Valve Implantation (TAVI), populations who were previously not fit enough for heart valve surgery are now able to have a valve replacement without placing these higher risk individuals through major surgery. Complication rates following TAVI have reduced over the last few years, but recent studies suggest that the incidence of several complications remains high. Avoiding complications is key to reducing costs associated with TAVI, which is important given that the procedure is already more expensive than other treatment options. An emerging strategy for patients undergoing TAVI is to identify pre-operative factors predictive of post-operative adverse outcomes. This commentary summarises three systematic reviews exploring moderating factors for adverse events after TAVI surgery, with the aim of identifying statistically and clinically significant factors associated with poor surgical outcomes and contextualise these factors within clinical practice.
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Hill et al. (2022) studied this question.
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