Why the study?
Coronary slow flow phenomenon is associated with angina and ACS, and procalcitonin correlates with atherosclerosis extent, but its relationship with coronary slow flow remained unknown.
Serum procalcitonin levels are not associated with the coronary slow flow phenomenon, whereas C-reactive protein levels are significantly elevated, suggesting a specific inflammatory pathway involvement.
May link procalcitonin to slow flow; hypothesis-generating and should not yet change practice.
Objective: Coronary slow flow phenomenon is associated with angina pectoris and acute coronary syndromes. Procalcitonin levels are correlated with the extent of atherosclerosis in patients with coronary artery disease. We aimed to evaluate the relationship between procalcitonin and coronary slow flow phenomenon.Material and Method: The present study included 50 patients with coronary slow flow and 42 healthy subjects. The coronary slow flow phenomenon is defined as delayed coronary opacification in the absence of obstructive coronary artery disease. Coronary slow flow is evaluated with Thrombolysis in Myocardial Infarction frame count method. The Procalcitonin was calculated from the blood to analyze. Results: The C-reactive protein was significantly higher in the coronary slow flow group than the control group. There was a positive and significant correlation between the Mean Thrombolysis in Myocardial Infarction frame count and CRP levels. There were no correlations between the C-reactive protein and procalcitonin levels (r= -0.134, p= 0.204). Conclusion: Serum procalcitonin level was not associated with coronary slow flow. We have shown the relationship between serum C-reactive protein and coronary slow flow.
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Asoğlu et al. (2019) studied this question.
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