Why the study?
What is the mechanism of reduced forward stroke volume in children and swine with ventricular septal defect and failure to thrive?
Population
Children with ventricular septal defect and failure to thrive, children with VSD and normal growth, normal…
Authors
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Preload-focused strategies may merit exploration in VSD-FTT; leaves open confirmation in larger or randomized cohorts.
What is the mechanism of reduced forward stroke volume in children and swine with ventricular septal defect and failure to thrive?
Reduced forward stroke volume in children with VSD and failure to thrive is likely due to inadequate increase in end-diastolic volume rather than impaired contractility.
Corin et al. (1988) studied this question.
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