Detection of IL-36γ through noninvasive tape stripping reliably discriminates psoriasis from atopic eczema

Inflammatory skin reactions, regardless of their distinct underlying pathophysiologic mechanisms, can often present with similar morphology. Although typical eczema and lesions of plaque psoriasis are easily distinguishable by experienced dermatologists, these 2 diseases often cause diagnostic difficulties when inflammation is minimal or located in certain anatomical regions, including flexures, the scalp, auricular or palmoplantar areas. In these cases diagnosis can be problematic, in particular in the primary care setting, where misdiagnosis can lead to delayed appropriate treatment, overuse of antibiotics, or both.