April 28, 2003Archives of Internal Medicine

The Outpatient Bleeding Risk Index

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Why the study?

Does the Outpatient Bleeding Risk Index accurately predict major hemorrhage risk in patients treated for DVT or PE?

Structured PICO

Does the Outpatient Bleeding Risk Index accurately predict major hemorrhage risk in patients treated for DVT or PE?

Population

Consecutive patients objectively diagnosed with pulmonary embolism or deep venous thrombosis undergoing standard anticoagulant therapy (minimum 5 days of low-molecular-weight heparin overlapped with warfarin, followed by warfarin for at least 3 months with target INR 2.5).

Intervention

Risk stratification using the Outpatient Bleeding Risk Index.

Outcome

Major hemorrhages.safety

The Outpatient Bleeding Risk Index successfully discriminates between low and moderate bleeding risk in patients receiving anticoagulation for VTE, potentially guiding therapy duration.

Limitations

Only 2 patients were in the high-risk group, preventing definition of the bleeding rate for this category.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Supports VTE bleeding risk stratification with the index; leaves open prospective validation before guiding therapy.

Cite This Study

Wells et al. (2003) studied this question.

synapsesocial.com/papers/6a70b8d0e71d69abee08cc57 https://doi.org/10.1001/archinte.163.8.917

Topics

Pulmonary embolism Anticoagulation in AF

View Full Paper

Ask AI

Bookmark

The Outpatient Bleeding Risk Index

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

The Outpatient Bleeding Risk Index

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider