3D-Printed Patient-Specific Models of the Aortic Arch for Advanced Visualization of Complex Neurointerventional Cases

Background: Cerebrovascular disease is a leading cause of death and disability worldwide, and endovascular therapies have become a mainstay of treatment for ischemic stroke. However, tortuous anatomy, particularly of the aortic arch, presents formidable treatment challenges by impeding access to intracranial circulation and thus affecting clinical outcomes. Methods: To better understand the challenges of tortuous anatomy, we fabricated 3D-printed models of the aortic arch and major branch vessels based on the imaging of 4 patients. Results: These patient-specific models were realistic representations of the intricate vascular pathways and provided enhanced visualization of the complex vascular structures. The measured diameters of the 3D-fabricated models closely matched the values reported in the literature, confirming the physical accuracy of the models. Creating an individual anatomic model required an average of 4 hours of digital processing and 13.71 hours of 3D printing, with a materials cost of approximately $17.31. Conclusion: 3D-printed patient-specific models used for neurointerventional training and preprocedural planning are a valuable tool for managing complex cerebrovascular anatomy. The advanced visualization provided by these models may enhance preparedness and potentially improve ischemic stroke treatment outcomes.