Why the study?
Does the aortic valve-sparing David I procedure provide acceptable long-term survival and freedom from valve replacement in patients requiring aortic root surgery?
Does the aortic valve-sparing David I procedure provide acceptable long-term survival and freedom from valve replacement in patients requiring aortic root surgery?
The David I aortic valve-sparing procedure demonstrates acceptable long-term survival and freedom from valve replacement up to 10 years, with exceedingly low rates of stroke or major bleeding.
Answers are grounded in this paper and cite their sources.
Supports David I in selected aortic root cases; leaves open randomized comparisons to valve replacement.
OBJECTIVE: Aortic valve-sparing David procedure has gained broad acceptance. However, few long-term results have been published. We present our results. METHODS: More than 450 David procedures have been performed in our institution so far. Of these, 126 patients were operated between July 1993 and December 2000. Median age was 57 (8-83) years and 46 (36.5%) were female. As many as 26 (20.6%) had Marfan syndrome, 21 (16.7%) had acute aortic dissection type A (AADA) and 67 (53.2%) had additional procedures. RESULTS: There were six (4.8%) deaths in 30 post-operative period (POD), four of whom had AADA. In the follow-up, there were 32 (25.4%) late deaths, 11 (34.4%) of these were caused by cardiac or underlying disease or op-related. As many as 15 (11.9%) patients were re-operated; six (40%) were Marfan patients and two (13.3%) had early endocarditis. Follow-up echocardiography of 76 (60.3%) event-free patients showed valve insufficiency (AI)≤AI I° in 68 (89.5%) and grade II in 7 (9.2%) patients. Leaflet degeneration due to proposed leaflet contact with the straight Dacron graft was not observed. A total of 36 (47.4%) patients were in New York Heart Association (NYHA) class I, 33 (43.4%) in NYHA II, and five (6.6%) were in class III. During the entire follow-up of 790 patient-years, there was no stroke or major bleeding. Survival at 1, 5 and 10 years was 93%, 85% and 70%, respectively. Freedom from valve replacement at 1, 5 and 10 years was 96%, 91% and 87%, respectively. CONCLUSIONS: Regardless of the underlying pathology, valve-sparing David I procedure has acceptable long-term results. Valve-related complications such as stroke or major bleeding is exceedingly low.
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Shrestha et al. (2011) studied this question.
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