INTRODUCTION: Sclerotherapy in all its current forms is based on experience going back to the 1850s. METHODS: To trace the evolution of sclerotherapy over the past 250 years, using the internet for past documentation and the literature. CONCLUSION: Sclerotherapy principles were established long ago, although current modifications have been made possible by the introduction of detergent sclerosants and ultrasound guidance.
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Kenneth A. Myers (2018) studied this question.
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