The majority (approx. 80%) of infant acute lymphoblastic leukemia (ALL) cases are characterized by chromosomal rearrangements involving the Mixed Lineage Leukemia ( MLL , or KMT2A ) gene, which confer a poor prognosis: chances of event-free survival are 30–40% at best.[1][1] We and others showed
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Kerstjens et al. (2018) studied this question.