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The effect of Japanese green tea extract and various phenolic components of green tea on nitrosamine formation in vitro were investigated. We found that green tea extract seems to enhance the nitrosation of four secondary amines under acidic conditions; however, there exists an optimum concentration for the catalytic effect on nitrosamine forma ion. Among various polyphenols in Japanese green tea, only catechins catalyze nitrosamine formation, while pyrocatechol, pyrogallol, and gallic acid inhibit the reaction. No significant effect on the nitrosation reaction could be observed in the presence of either flavonols or flavones.
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Nakamura et al. (1981) studied this question.
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