Key result
Chronic liver disease significantly alters stroke risk, underlying mechanisms, and optimal management strategies.
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Chronic liver disease (CLD) is a highly prevalent condition. There is burgeoning recognition that there are many people with subclinical liver disease that may nonetheless be clinically significant. CLD has a variety of systemic aberrations relevant to stroke, including thrombocytopenia, coagulopathy, elevated liver enzymes, and altered drug metabolism. There is a growing body of literature on the intersection of CLD and stroke. Despite this, there have been few efforts to synthesize these data, and stroke guidelines provide scant guidance on this topic. To fill this gap, this multidisciplinary review provides a contemporary overview of CLD for the vascular neurologist while appraising data regarding the impact of CLD on stroke risk, mechanisms, and outcomes. Finally, the review addresses acute and chronic treatment considerations for patients with stroke-ischemic and hemorrhagic-and CLD.
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Parikh et al. (2023) conducted a review in Stroke in patients with chronic liver disease. Chronic liver disease was evaluated. Chronic liver disease impacts stroke risk, mechanisms, and acute and chronic treatment considerations, though no quantitative data are reported in the abstract.
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