According to the World Health Organization, preeclampsia is one of the leading causes of maternal and fetal morbidity and mortality in developing countries. The aim was to evaluate whether an association exists between vitamin D deficiency and preeclampsia in Al-Jabal Al-Akhdar, Libya. A total of 158 pregnant women, ranging in gestational age from 27 to 40 weeks, were included in the study. Each participant had their vitamin D level measured, and then they were categorized into two groups: control and preeclampsia. The preeclampsia cases were further divided into mild and severe preeclampsia. Patients with preeclampsia had lower serum vitamin D levels than the control group. A logistic regression analysis revealed no significant difference in serum vitamin D levels between preeclampsia and control groups. The total odds ratios for the preeclampsia group were not statistically significant. The preeclampsia group showed an OR of 2.457 (95% CI: 1.330 to 4.541), which suggests a statistically significant increased risk. Patients with preeclampsia had lower serum vitamin D levels than the control group, vitamin D deficiency may be associated with an increased risk of severe preeclampsia.
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Alsaliheen et al. (2026) studied this question.
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