Influenza virus A can simultaneously cause fulminant myocarditis and Guillain-Barré syndrome, which can be successfully managed with mechanical circulatory support followed by immunoadsorption.
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Alerts clinicians to monitor for myocarditis in influenza patients with prior GBS; leaves open questions on triggers and management.
We herein report the case of a 47-year-old woman who was admitted with weakness and numbness of the limbs and dyspnea after being infected with influenza virus A. She had a history of Guillain-Barré syndrome (GBS) 7 years prior to this presentation. On admission, she was in shock, and transthoracic echocardiography showed severely reduced left-ventricular function. She was diagnosed with fulminant myocarditis by an endomyocardial biopsy, which was complicated by GBS. Venoarterial extracorporeal membrane oxygenation was required to manage the cardiogenic shock. After her condition improved, immunoadsorption for GBS was performed, and the motor and sensory disorders gradually improved.
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Morita et al. (2020) studied this question.
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