Why the study?
Does switching to fondaparinux and edoxaban improve thrombus resolution in a young patient with acute pulmonary embolism refractory to unfractionated heparin?
Does switching to fondaparinux and edoxaban improve thrombus resolution in a young patient with acute pulmonary embolism refractory to unfractionated heparin?
Switching from unfractionated heparin to fondaparinux and subsequently edoxaban led to rapid thrombus resolution in a young patient with acute massive pulmonary embolism and giant uterine leiomyoma.
May support edoxaban in select high-PE-risk DVT; hypothesis-generating and leaves open need for RCTs.
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Kiyoaki Niimi (2016) studied this question.
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