Osteoporosis poses a significant challenge in spinal fusion surgery by compromising bone quality and increasing the risk of complications. This article reviews the impact of osteoporosis on fusion outcomes and evaluates the efficacy of both antiresorptive and anabolic agents in enhancing bone strength. It also outlines practical strategies for preoperative assessment and personalized perioperative treatment to improve surgical success in osteoporotic patients.
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Lui et al. (2025) studied this question.
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