Key result
Normal-renin hypertension is linked to lower plasma and extracellular fluid volumes vs normotensive controls.
Case-Control (n=60)
Erythrocyte mass, plasma volume (PV), extracellular fluid volume (ECFV) and total body water were simultaneously measured in 30 normotensive and 30 normal-renin hypertensive Caucasian male subjects for accurate determination of the presence or absence of a disorder(s) in body-fluid composition in hypertension. 2. The results indicate that plasma volume and total blood volume are lower in hypertensive subjects than in normotensive control subjects. The PV comprised 19% of the ECFV in both control and hypertensive subjects. 3. ECFV was lower in hypertensive subjects than in normotensive control subjects; the PV and interstitial fluid components of the ECFV were reduced by similar proportions. The ECFV, furthermore, comprised a smaller portion of the total body water in hypertensive subjects than that in control subjects. 4. We conclude that in the hypertensive state there is a reduction in the ECFV, but that there is no change in the partition of the ECFV between the plasma and interstitial components.
No takes yet. Share an insight, caveat, or question.
Bauer et al. (1982) conducted a case-control in Hypertension (n=60). Normal-renin hypertension vs. Normotensive control was evaluated on Body-fluid composition (erythrocyte mass, plasma volume, extracellular fluid volume, and total body water). Normal-renin hypertension was associated with lower plasma and extracellular fluid volumes vs normotensive controls, though plasma volume remained 19% of extracellular fluid volume in both groups.
Synapse has enriched 5 related papers. Consider them for comparative context: