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July 1, 2001Journal of Biological ChemistryOpen Access

The Selectivity Filter of the Voltage-gated Sodium Channel Is Involved in Channel Activation

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KHKarlheinz HilberWSWalter SandtnerOKOliver Kudlacek

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Hilber et al. (2001) studied this question.

synapsesocial.com/papers/6a70c9cc2fdcb5703edb6840https://doi.org/10.1074/jbc.m101933200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison between slow sodium channel inactivation in rat slow‐ and fast‐twitch muscle.1987 · 73 citations
  2. 2Sodium channel selectivity filter regulates antiarrhythmic drug binding1997 · 118 citations
  3. 3Functional availability of sodium channels modulated by cytosolic free Ca2+ in cultured mammalian neurons (N1E‐115).1995 · 13 citations
  4. 4A Structural Rearrangement in the Sodium Channel Pore Linked to Slow Inactivation and Use Dependence2000 · 103 citations
  5. 5Functional association of the beta 1 subunit with human cardiac (hH1) and rat skeletal muscle (mu 1) sodium channel alpha subunits expressed in Xenopus oocytes.1995 · 132 citations