This is the first reported case of an arterial tumour-thrombus causing acute arterial occlusion in a patient with relapsed osteosarcoma.
Answers are grounded in this paper and cite their sources.
Tumor-thrombus should be considered in osteosarcoma patients with acute ischemia on regorafenib; single case leaves open any causal link.
We describe a 21-year-old male patient with a history of relapsed osteosarcoma who presented with symptoms consistent with acute right lower limb ischaemia. He had received 7 cycles of palliative Regorafenib 160 mg once daily. Imaging demonstrated an occluded abdominal aorta. Histopathology of a resected thrombus cast revealed metastatic tumour-thrombus. Re-perfusion of his lower limb was achieved. This case report emphasises the importance of inter-professional collaboration in managing patients with rare cancers who present as an emergency. To our knowledge, this is the first case reporting an arterial tumour-thrombus in a patient with relapsed osteosarcoma.
No takes yet. Share an insight, caveat, or question.
Kidd et al. (2025) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: