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Reveals three hyperinvasive Neisseria meningitidis serogroup C clonal complexes causing disease clusters in regional populations, highlighting links to high case-fatality rates.
During 2003-2012, 8 clusters of meningococcal disease were identified in Rio de Janeiro State, Brazil, all caused by serogroup C Neisseria meningitidis. The isolates were assigned to 3 clonal complexes (cc): cc11, cc32, and cc103. These hyperinvasive disease lineages were associated with endemic disease, outbreaks, and high case-fatality rates.
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Barroso et al. (2013) studied this question.
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