Why the study?
The optimal perioperative oxygen concentration remains debated, especially regarding absorption atelectasis, surgical site infections, and revised WHO guidelines recommending 80% oxygen under general anesthesia.
Does high fraction of inspired oxygen (e.g., 80-100%) during induction and maintenance of anesthesia prevent surgical site infection or cause harm in surgical patients undergoing general anesthesia?
Does high fraction of inspired oxygen (e.g., 80-100%) during induction and maintenance of anesthesia prevent surgical site infection or cause harm in surgical patients undergoing general anesthesia?
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Routine administration of high perioperative oxygen (80-100%) lacks clear evidence for preventing surgical site infections and may cause absorption atelectasis and oxidative stress, challenging previous WHO guidelines.
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Shuya Kiyama (2022) studied this question.
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