Heterogeneous Nucleation in Droplet-Based Nucleation Measurements

Droplet-based nucleation experiments reveal discrepancies in kinetic and thermodynamic factors. Here we examine how the chemical nature of the water–oil interface, and not the type of the device, used in different set-ups by three different groups impacts nucleation rate and explain discrepancies among lysozyme interfacial energies and pre-exponential factors encountered in the literature.