Why the study?
Are depressive disorders associated with higher frequencies and intensities of symptoms in hospitalized patients with advanced cancer?
Are depressive disorders associated with higher frequencies and intensities of symptoms in hospitalized patients with advanced cancer?
Depressive disorders are highly prevalent in hospitalized advanced cancer patients and are associated with increased symptom burden.
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May warrant depression screening in advanced cancer inpatients; leaves open effects on symptom control and outcomes.
AIM: To explore the frequencies and intensities of depressive symptoms associated with hospitalized patients with advanced cancer. METHODS: test and Wilcoxon rank-sum test were used to compare the frequency and intensity of symptoms between patients with and without depressive disorders. Spearman rank correlation was used to test the correlation between depression and symptoms. RESULTS: Of the 196 enrolled patients, 115 (59%) were males. The median age of the patients was 58 (19-80) years. Seventy-six (39%) patients were diagnosed with depression (SDS ≥ 53). Patients with depressive disorders exhibited pain, drowsiness, and nausea along with a higher frequency and intensity of poor self-perception, appetite loss, anxiety, dyspnea, and fatigue. Depressive symptoms were positively correlated with the symptoms. CONCLUSION: Depressive disorders are very common and severe in hospitalized patients with advanced cancer. Identifying the frequencies and intensities of the symptoms enables early intervention to improve patients' quality of life.
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Liu et al. (2016) studied this question.
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