Regeneration and Repair After Biologic Treatment of Root Surfaces in Monkeys: II. Proximal Surfaces Posterior Teeth,,

THE HEALING of a new attachment procedures was evaluated in monkeys. Standard flap curettage procedures were made in posterior segments having previously created periodontal pockets. The diseased root surfaces were treated with sodium deoxycholate (2%) and human plasma fraction Cohn IV1 (5%), applied to experimental sites for 1 minute each. Control surfaces were similarly treated with phosphate buffered saline. The healing at 10 weeks postoperatively was described clinically, histologically, and by histometrics. There was a significant increase in connective tissue new attachment in experimental sites, compared to controls.