Surveys for the prevalence of chloroquine resistant P. falciparum were carried out in north, central and south Thailand. The frequency of unsatisfactory response to 1500 mg. of chloroquine base ranged from a high of 85% to a low of 6% in different areas. In a series of hospital patients 37·5% had a poor clinical response and 25% an inadequate parasitological response.
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Cadigan et al. (1968) studied this question.