Lymphosarcoma

The purpose of this investigation was to correlate the clinical, roentgenologic and pathologic observations on a group of patients suffering from lymphosarcoma, with special emphasis on the differential diagnosis and the radiosensitivity of the associated mediastinal lesions. In order to be of value a study of this type should fulfil several conditions: The clinical observations must be controlled by pathologic data; the ultimate fate of the patient must be known, and in case of death there must be a control by autopsy. All these conditions are fulfilled in this investigation. The material on which this analysis is based consists of 30 cases of microscopically proved lymphosarcoma. The end-result is known in every case, constituting 100 per cent follow-up, and an autopsy was performed on each of the 13 patients who died in the hospital. One of the most interesting and largely unexplained features of neoplastic diseases is the marked variations