The Metabolic Syndrome as a Predictor of Nonalcoholic Fatty Liver Disease

Letters7 March 2006The Metabolic Syndrome as a Predictor of Nonalcoholic Fatty Liver DiseaseMasahide Hamaguchi, MD, Noriyuki Takeda, MD, and Takao Kojima, MDMasahide Hamaguchi, MDFrom Asahi University Murakami Memorial Hospital, Gifu 500-8523, Japan.Search for more papers by this author, Noriyuki Takeda, MDFrom Asahi University Murakami Memorial Hospital, Gifu 500-8523, Japan.Search for more papers by this author, and Takao Kojima, MDFrom Asahi University Murakami Memorial Hospital, Gifu 500-8523, Japan.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-144-5-200603070-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Drs. Chavez-Tapia, Mendez-Sanchez, and Uribe argue that our study's lack of a second ultrasonographic evaluation by a different reviewer restricts the accuracy of the diagnosis of NAFLD. We understand that ultrasonography is not a perfect test and may lead to an incorrect diagnosis of NAFLD in many patients. However, as reported in the reference they quoted (1), interobserver variability is much greater than intraobserver variability for evaluation of the pattern and severity of NAFLD. The inclusion of a second reviewer would have decreased the power to detect longitudinal changes of ultrasonographic images. We believe that ultrasonographic interpretation by ...References1. Saadeh S, Younossi ZM, Remer EM, Gramlich T, Ong JP, Hurley M, et al. The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology. 2002;123:745-50. [PMID: 12198701] CrossrefMedlineGoogle Scholar2. Ford ES, Mokdad AH, Giles WH. Trends in waist circumference among U.S. adults. Obes Res. 2003;11:1223-31. [PMID: 14569048] CrossrefMedlineGoogle Scholar3. Shiwaku K, Anuurad E, Enkhmaa B, Nogi A, Kitajima K, Yamasaki M, et al. Predictive values of anthropometric measurements for multiple metabolic disorders in Asian populations. Diabetes Res Clin Pract. 2005;69:52-62. [PMID: 15955387] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Asahi University Murakami Memorial Hospital, Gifu 500-8523, Japan.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Metabolic Syndrome as a Predictor of Nonalcoholic Fatty Liver Disease Masahide Hamaguchi , Takao Kojima , Noriyuki Takeda , Takayuki Nakagawa , Hiroya Taniguchi , Kota Fujii , Tatsushi Omatsu , Tomoaki Nakajima , Hiroshi Sarui , Makoto Shimazaki , Takahiro Kato , Junichi Okuda , and Kazunori Ida The Metabolic Syndrome as a Predictor of Nonalcoholic Fatty Liver Disease Norberto C. Chavez-Tapia , Nahum Mendez-Sanchez , and Misael Uribe The Metabolic Syndrome as a Predictor of Nonalcoholic Fatty Liver Disease Yujiro Kida and Tetsuji Sato Metrics Cited ByCorrelation between computed tomography adapted leaman score and computed tomography liver and spleen attenuation parameters for non-alcoholic fatty liver disease as well as respective inflammatory mediators 7 March 2006Volume 144, Issue 5Page: 380KeywordsAdipokinesBody mass indexConflicts of interestGastroenterology and hepatologyLongitudinal studiesMetabolic disordersMetabolic syndromeNon-alcoholic fatty liver diseaseObesityUltrasound imaging ePublished: 7 March 2006 Issue Published: 7 March 2006 CopyrightCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...