Key result
Pre-hospital ECG and paramedic thrombolysis reduce treatment delays, morbidity, and mortality in acute MI.
Why the study?
Because rapid diagnosis and thrombolysis reduce morbidity and mortality in acute myocardial infarction, strategies that improve pre-hospital time to treatment are of fundamental importance.
Does estrogen replacement therapy reduce the risk for dementia due to Alzheimer's disease in postmenopausal women?
Does estrogen replacement therapy reduce the risk for dementia due to Alzheimer's disease in postmenopausal women?
Answers are grounded in this paper and cite their sources.
While biological mechanisms and observational data suggest estrogen replacement therapy may protect against Alzheimer's disease, definitive evidence from randomized trials is still needed.
In this paper, we discuss and critically analyse pre-hospital management of acute myocardial infarction (AMI). It is clear from several large studies that rapid diagnosis and application of thrombolysis reduces morbidity and mortality rates. Strategies that improve time to treatment in the pre-hospital setting are therefore of fundamental importance in the management of this fatal disease. The advantage of 12 lead electrocardiography use by paramedics to diagnose AMI and reduce time to treatment is discussed. Moreover, paramedic application of thrombolysis in the pre-hospital environment is examined. Several studies conducted worldwide support the notion that ambulance services can play a role in minimising time to treatment for patients with AMI. The contribution of early intervention by paramedics trained in critical care is potentially considerable, particularly in the important chain of survival that is often initiated by pre-hospital intervention.
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S. Claiborne Johnston (2006) conducted a review in Acute myocardial infarction (AMI). Pre-hospital 12-lead electrocardiography and thrombolysis by paramedics was evaluated on Time to treatment, morbidity, and mortality rates. Pre-hospital 12-lead electrocardiography and thrombolysis by paramedics can reduce time to treatment, morbidity, and mortality in acute myocardial infarction (no quantitative data reported).
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