The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, diethyl malonate, P2O5, piperidine, and chlorobenzene with a commercial microwave oven. Six Knoevenagel condensation products were synthesized within 5–15 min in good yields.
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Kim et al. (1996) studied this question.
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