Key result
Changing host factors and modern cardiac interventions are shifting the epidemiological profile of bacterial endocarditis.
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IN recent years there have been changes in many of the factors which influence the development and outcome of bacterial endocarditis. These changes relate to both the susceptible host and the causative organism. Rheumatic fever, for example, appears to be declining in incidence and severity.1 , 2 More cases of bacterial endocarditis are being encountered in elderly persons with no history of valvular disease or murmurs.3 In addition, many more patients are being treated with corticosteroid hormones, immunosuppressive agents and extensive radiotherapy, all of which interfere with normal mechanisms of host resistance.4 , 5 The use of newly developed technics in cardiac surgery, such . . .
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Uwaydah et al. (1965) conducted a review in Bacterial endocarditis. Host factors such as declining rheumatic fever, advanced age, immunosuppressive therapy, and new cardiac surgery techniques are altering the epidemiological pattern of bacterial endocarditis.
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