Chloromycetin in the Treatment of Salmonella Enteritis

SALMONELLA infections have shown a singular refractoriness to chemotherapeutic and antibiotic agents thus far. The inability of sulfonamides to affect favorably the course of the disease is now well established.1 During the past year, 8 cases of salmonella enteritis were treated at Children's Hospital, Washington, D. C, with streptomycin in large doses.2 Only 1 patient was rendered permanently free of salmonella; in the other 7 cases, the organism reappeared in the stools after discontinuation of therapy. Seligmann et al.3 have similarly reported a series of 5 cases of salmonella enteritis in infants in whom streptomycin failed to produce a permanent . . .