March 1, 2001Arteriosclerosis Thrombosis and Vascular BiologyOpen Access

Accumulation of Triglyceride-Rich Lipoprotein in Subjects With Abdominal Obesity

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Population

Subjects with abdominal obesity selected on the basis of a high waist-to-hip ratio, representing patients…

Design

Cross-sectional

Authors

JBJean‐Marie BardNantes Université MCMarie‐Aline CharlesDélégation Paris 5 IJI. Juhan‐VagueGeneral / Preventive / Lipids

Discussion

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Implication

Insulin and remnant markers may contribute to triglycerides in obesity; cross-sectional data leave causality and PAI-1 specificity open.

Structured PICO

Population

Subjects with abdominal obesity selected on the basis of a high waist-to-hip ratio (≥0.95 for men and ≥0.80 for women), representing patients with insulin resistance from the BIGPRO 1 study population at inclusion.

Outcome

Relationship between markers of remnant accumulation (apoC-III LpB and apoE LpB), insulin, and plasma triglyceride concentration.surrogate

In subjects with abdominal obesity and insulin resistance, increased insulin levels are associated with an increased production of triglyceride-rich lipoproteins enriched in apoC-III and apoE, contributing to hypertriglyceridemia.

Cite This Study

Bard et al. (2001) studied this question.

synapsesocial.com/papers/6a70e88431a3df824329282e https://doi.org/10.1161/01.atv.21.3.407

Topics

Women and heart disease

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Accumulation of Triglyceride-Rich Lipoprotein in Subjects With Abdominal Obesity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Accumulation of Triglyceride-Rich Lipoprotein in Subjects With Abdominal Obesity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider