The Role of Hemogram Parameters in Predicting the Severity of Pulmonary Embolism

The study, which was planned as a retrospective cohort, was followed up with the diagnosis code ICD-10 "I26" in our service between January 1, 2017 and July 1, 2020, the data could be accessed from the electronic patient information system, the diagnosis of PE was confirmed by Introduction: Acute pulmonary embolism (PE) is a disease with serious mortality and morbidity. Therefore, early diagnosis and treatment are important. A PE is a process accompanied by inflammation. Therefore, our study was designed to examine the relationship between hemogram parameters, which are easily accessible and indicative of inflammation, and late mortality from PE. Methods: Two hundred and two patients who were hospitalized in our hospital between January 1, 2017 and July 1, 2020 and who were diagnosed with pulmonary angio computed tomography were included. Demographic and clinical data, laboratory, radiology and echocardiography results of the patients were analyzed retrospectively from the hospital information system. Results: Seventy-eight of 202 patients included in the study were male (38.6%), 124 females (61.4%), mean age was 58.2716.26 years. According to the results of univariate Cox regression analysis, age [hazard ratio (HR): 1,058, p=0.001], D-dimer (HR: 1,057, p=0.015), presence of malignancy (HR: 6,274, p=0.001), trauma history ( HR: 2,931, p=0.039), long travel history (HR: 0.163, p=0.003), C-reactive protein (HR: 1,004, p=0.021), PE severity index (HR: 1,033, p=0.001), EF (HR: 0.944 , p=0.001), red-cell distribution width (HR: 1,125, p=0.001), lymphocyte (HR: 0.999, p=0.001), platelet-lymphocyte ratio (PLR) (HR: 1.013, p=0.001) and neutrophil-lymphocyte ratio (NLR) (HR: 1,017, p=0.001) significantly and it was associated with mortality.