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April 1, 1997Infection and ImmunityOpen Access

Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis

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Authors

BHBéate HeymGroupe Hospitalier Diaconesses Croix Saint-SimonESEvangelos StavropoulosThe Francis Crick InstituteNHNadine HonoréInstitut Pasteur

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Heym et al. (1997) studied this question.

synapsesocial.com/papers/6a70f1ba6c240de38cdbff09https://doi.org/10.1128/iai.65.4.1395-1401.1997
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Also Consider

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  3. 3Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis1996 · 120 citations
  4. 4Mechanistic Studies of the Oxidation of Isoniazid by the Catalase Peroxidase from Mycobacterium tuberculosis1994 · 280 citations
  5. 5Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative‐stress regulatory gene:implications for sensitivity to isoniazid1995 · 179 citations