Answers are grounded in this paper and cite their sources.
Ultrafiltrates of human myoglobin from 200 individuals were examined by starch-gel electrophoresis. Only two variants, Mb Aberdeen and Mb Annapolis , of the commonly occurring myoglobin Mb + were encountered. Each variant is apparently inherited as an autosomal codominant. Heterozygotes for either mutation lack apparent muscular disease. Combined electrophoresis and chromatography of Mb Annapolis indicate a loss of arginine at a position near the C-terminal portion of the molecule.
No takes yet. Share an insight, caveat, or question.
Boyer et al. (1963) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: