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IN A previous review,1 evidence by pathologists for the origin of venous thrombosis below the knees was presented. Serious illnesses, especially cardiac, injuries, operations and childbirth were proved to be the usual background for thrombosis, much of which was terminal and unnoticed clinically. The state of the blood platelets following childbirth and surgical operations was shown to predispose toward thrombosis, and patients might be more or less liable to it, as indicated by their tolerance for or sensitivity to heparin. Local conditions in the lower limbs, however, appeared to be more important factors than any others. Early ambulation did not . . .
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John Homans (1946) studied this question.
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