Why the study?
Does cryoballoon ablation increase the isolated surface area compared to laser balloon ablation in patients undergoing pulmonary vein isolation?
Does cryoballoon ablation increase the isolated surface area compared to laser balloon ablation in patients undergoing pulmonary vein isolation?
Cryoballoon ablation results in a larger acute isolated surface area compared to laser balloon ablation during PVI, though this did not impact mid-term clinical recurrence in this small cohort.
CB yields larger acute ISA than LB; leaves open effects on durability and long-term PVI success.
BACKGROUND: Clinical outcome after pulmonary vein isolation (PVI) may be linked to both durability of PVI and the antral lesion size. Data on balloon-guided technologies are scarce. We investigated the size of the isolated surface area (ISA) acutely after PVI achieved by cryoballoon (CB) or laser balloon (LB), both using voltage mapping. METHODS AND RESULTS: ; P=0.002) as well as ISA (65±8% vs. 54±10%; P=0.001) were significantly larger in the CB than in the LB group. No periprocedural complications occurred. During a mean follow-up of 326±142 days, 4/20 and 5/20 patients experienced an AF/AT recurrence in the CB and LB groups, respectively. No differences in clinical outcome were observed between patients with a large (≥55%) or small (<55%) ISA. CONCLUSIONS: Balloon-guided PVI is associated with antral lesion formation. CB-guided PVI is associated with the largest ISA as compared with LB procedures. ISA size did not correlate with clinical outcome after a single procedure in the present study population.
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Perrotta et al. (2016) studied this question.
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