Introduction 1. In the path of the hurricane: disease and the disappearance of the peoples of the Caribbean, 1492-1518 2. The deaths of Aztec Cuitlahuac and Inca Huayna Capac: the first New World pandemics 3. Settling in: epidemics and conquest to the end of the first century 4. Regional outbreaks from the 1530s to century's end 5. New arrivals: peoples and illnesses from 1600-1650 Conclusion.
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McNeill et al. (1999) studied this question.