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January 1, 1996BloodOpen Access

Human natural killer cell expansion is regulated by thrombospondin- mediated activation of transforming growth factor-beta 1 and independent accessory cell-derived contact and soluble factors

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Authors

BPBA PiersonUniversity of MinnesotaKGKalpna GuptaUniversity of California, IrvineWHW-S. HuUniversity of Minnesota

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Pierson et al. (1996) studied this question.

synapsesocial.com/papers/6a71047fb5c1fe5ca9dfc90fhttps://doi.org/10.1182/blood.v87.1.180.bloodjournal871180
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-beta.1994 · 253 citations
  2. 2Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.1986 · 1,595 citations
  3. 3Fc gamma R(CD16) interaction with ligand induces Ca2+ mobilization and phosphoinositide turnover in human natural killer cells. Role of Ca2+ in Fc gamma R(CD16)-induced transcription and expression of lymphokine genes.1989 · 207 citations
  4. 4Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system.1994 · 274 citations
  5. 5The generation of human natural killer cells from CD34+/DR- primitive progenitors in long-term bone marrow culture1992 · 163 citations