Relation of Staph. Pyogenes to Dental Caries

PREGNANCY COMPLICATED BY DIABETES MELLITUS X,There is a greater terfdency for the diabetic to develop late pregnancy toxaemia than the non-diabetic, and the relative incidence varies with the standard of severity of the toxaemia taken for comparison.The maternal prognosis is good, and pregnancy does not make the diabetes worse provided that it is well treated.The late foetal mortality was 55% in a first series of 43 pregnancies.'ln a second series of 15 pregnancies in which oestrogens were given there were only three deaths.The cause .of the foetal mortality is discussed, and it is suggested that the factor affecting the viability of the foetus probably arises in the maternal anterior pituitary lobe.The incidence of abortion does not appear to differ from that for non-diabetic pregnancies, and suggests, first, that diabetes mellitus is not a cause of abortion, and, secondly, that the factor which reduces foetal viability exerts its strongest influence towards the end of pregnancy.Congenital deformities, gigantism, and hypoglycaemia of the newborn are briefly discussed, and it is suggested that the tendency to gigantism is due to an excess of the growth hormone from the maternal pituitary gland.We should like to express our gratitude to Professor W. C. W. Nixon, Director of the Obstetric Unit, for his encouragement and permission to make use of the case records of the Obstetric Unit; to Professor H. P. Himsworth, Director of the Medical Unit, for permission to make use of the records of the Diabetic Clinic