Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 2, 2001The Journal of Cell BiologyOpen Access

The Inhibitor of Apoptosis Protein-Binding Domain of Smac Is Not Essential for Its Proapoptotic Activity

View Full Paper
Ask AI
Bookmark
Share

Authors

DRDarren L. RobertsManchester Academic Health Science CentreWMWendy MerrisonUniversity of LeicesterMMMarion MacFarlaneMRC Laboratory of Molecular Biology

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Roberts et al. (2001) studied this question.

synapsesocial.com/papers/6a710971439bab0cabc36d24https://doi.org/10.1083/jcb.153.1.221
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway2000 · 357 citations
  2. 2FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis1997 · 339 citations
  3. 3Processing/Activation of At Least Four Interleukin-1β Converting Enzyme–like Proteases Occurs during the Execution Phase of Apoptosis in Human Monocytic Tumor Cells1997 · 132 citations
  4. 4Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked1997 · 4,961 citations
  5. 5Active Caspases and Cleaved Cytokeratins Are Sequestered into Cytoplasmic Inclusions in Trail-Induced Apoptosis2000 · 157 citations