Why the study?
Does AFM intensive induction chemotherapy produce rapid tumor shrinkage in patients with metastatic breast cancer?
Population
45 patients with metastatic breast cancer
Design
Case_series
Follow-up
mean of 70 days on treatment
Authors
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AFM may support rapid responses in metastatic breast cancer; case-report data leave durability, toxicity, and generalizability open for prospective trials.
Does AFM intensive induction chemotherapy produce rapid tumor shrinkage in patients with metastatic breast cancer?
AFM is a highly effective but toxic induction regimen for metastatic breast cancer, achieving a 91% overall response rate.
Jones et al. (1990) studied this question.
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