What question did this study set out to answer?

The aim is to evaluate left ventricular wall motion using echocardiography in muscular dystrophy patients.

September 1, 1975CirculationOpen Access

Echocardiographic evaluation of posterior left ventricular wall motion in muscular dystrophy.

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Why the study?

Does echocardiographic evaluation of posterior left ventricular wall motion identify subclinical myocardial abnormalities in patients with muscular dystrophy?

Population

Patients with muscular dystrophy (n=22)

Comparison

Echocardiographic evaluation of maximal systolic… vs Age-matched normals, persons with myotonia…

Design

Cross-sectional

Authors

RKR B KovickWadsworth Center AFAlan M. FogelmanUniversity of Southern California AAA D Abbasi

Discussion

Member takes

Implication

May support echocardiographic screening for subclinical LV dysfunction in muscular dystrophy; leaves open impact on outcomes.

Key Points

The aim is to evaluate left ventricular wall motion using echocardiography in muscular dystrophy patients.
Echocardiographic measurements of systolic and diastolic endocardial velocities were taken.
Participants included muscular dystrophy patients and age-matched normal controls.
Systolic endocardial velocity (SEVM) was 5.5 +/- 0.9 cm/sec, significantly lower than in age-matched controls (P < 0.05).
Diastolic endocardial velocity (DEVM) was 13 +/- 3 cm/sec, significantly lower than all comparison groups (P < 0.001-0.05).
DEVM abnormalities were present despite normal clinical evaluations in 18 of 22 patients.

Structured PICO

Does echocardiographic evaluation of posterior left ventricular wall motion identify subclinical myocardial abnormalities in patients with muscular dystrophy?

Population

Patients with muscular dystrophy (n=22)

Intervention

Echocardiographic evaluation of maximal systolic endocardial velocity (SEVM) and maximal diastolic endocardial velocity (DEVM)

Comparator

Age-matched normals, persons with myotonia congenita, deconditioned patients, older normal persons, and persons with spinal muscular atrophy

Outcome

Maximal systolic endocardial velocity (SEVM) and maximal diastolic endocardial velocity (DEVM)surrogate

Echocardiographic measurement of diastolic endocardial velocity can detect subclinical myocardial relaxation abnormalities in muscular dystrophy patients before clinical symptoms or ECG changes appear.

Cite This Study

Kovick et al. (1975) studied this question.

synapsesocial.com/papers/6a710aabce524a4339c4ab97 https://doi.org/10.1161/01.cir.52.3.447

Topics

Echocardiography

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Echocardiographic evaluation of posterior left ventricular wall motion in muscular dystrophy.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Echocardiographic evaluation of posterior left ventricular wall motion in muscular dystrophy.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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