Key result
Cardiac membrane polyunsaturated fatty acid composition strongly influences isoproterenol-induced myocardial necrosis and mortality.
The fatty acid composition of cardiac membrane lipids is influenced by age, sex, diet and other factors. 2. The relative amounts of various polyunsaturated fatty acids in cardiac lipids influence markedly the development of myocardial necrosis and mortality following overstimulation with isoproterenol. 3. The availability and metabolism of arachidonic acid may play an important role in regulation of cardiac metabolism.
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Gudbjarnason et al. (1976) conducted a review in Cardiac necrosis. Cardiac membrane polyunsaturated fatty acids and isoproterenol overstimulation was evaluated on Myocardial necrosis and mortality. Polyunsaturated fatty acid composition in cardiac membrane lipids markedly influences myocardial necrosis and mortality following isoproterenol overstimulation.
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