Simple but effective! 8-Methoxyquinoline, an unsophisticated fluorophore, displays both 2:1 multiplexer and 1:2 demultiplexer digital functions (see picture). Protonation of the fluorophore results in completely different optical spectral profiles and multiplexing/demultiplexing behavior is obtained by exploiting the proton-driven reversible modulation of two complementary absorption and fluorescence signals.
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Amelia et al. (2008) studied this question.
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